The house no. 126 used to belong among the most important buildings of the Kolín ghetto, as it was used as a Jewish school since 1654. Its original medieval core consists of a visually different left part, which is decorated with a late Baroque façade from the second half of the 18th century. After 1782, the original school building began to be used as the rabbi’s home. In 1844-1846, a new classicist school building was added to the house on the location of the alley leading to the synagogue, which forms the right part of the building. On the front façade there is a memorial plaque dedicated to more than 2,200 members of the Jewish community deported from the former Kolín Oberlandrat during the Second World War. Only 135 of them lived to see the end of the war. The synagogue, which is one of the oldest and most valuable monuments of its kind in the Czech Republic, is accessible through an entryway on the ground floor of the House no 157.

Its existence is documented already before the year 1422. The house owes its present early Baroque appearance to the reconstruction completed in 1696. In 1721 and 1815 the synagogue was significantly enlarged by additions of the premises on the sides. It served its original purpose until the actual dissolution of the Jewish community in Kolín in 1953. The interior preserves early Baroque stucco decoration and the ornamental Torah ark (aron ha-kodesh) from the end of the 17th century.